Even their women exchanged natural relations for unnatural ones: In this context, the natural way refers to the nature of the world as God made it.
As in the Old Testament, Paul refers to same-sex sexual behavior as one example of how people have turned away from honoring the true God (see Genesis 19:1–28; Leviticus 18:22; Leviticus 20:13; Deuteronomy 23:17–18).
God created human beings as male and female, and engaging in same-sex sexual activity is a violation of God’s creative intention.